D'Alonzo RC, et al. Chapter 5 - Three Dimensional Transesophageal Echocardiographic Planning. Robotic Cardiothoracic Surgery: Atlas and Guide. WR Chitwood and K Kernstein eds. (In press)
D'Alonzo RC, et al. Chapter 4 – Anesthesia for Robotic Cardiac Surgery. Robotic Cardiothoracic Surgery: Atlas and Guide. WR Chitwood and K Kernstein eds. (In press)
D'Alonzo RC, et al. (2011) A randomized, double blind, placebo controlled clinical trial of the preoperative use of ketamine for reducing inflammation and pain after thoracic surgery. J Anesth. 25(5); 672-8.
D'Alonzo RC, et al. (2010) Percutaneous coronary sinus catheter placement aided by 3-dimensional transesophageal echocardiography. Anesth Analg.110:722-4.
D'Alonzo RC, et al. (2009) A retrospective comparison of anesthetic management of robot-assisted laparoscopic radical prostatectomy versus radical retropubic prostatectomy. J Clin Anesth.21:322-8
D'Alonzo RC, et al. (2008) Ethnicity and the distance to the epidural space in parturients. Reg Anesth Pain Med.33:24-29.
Steven Hill and Richard D'Alonzo. (2008) Chapter 27 - Perioperative Management of Bleeding and Transfusion. Perioperative Medicine: Managing for Outcome. Saunder, Elsevier, Philadelphia, PA. Editors – MF Newman, LA Fleisher, and MP Fink: 405-430.
D'Alonzo, R. C., et. al. (2002). Regulation of Collagenase-3 and Osteocalcin Gene Expression by Collagen and Osteopontin in Differentiating MC3T3-E1 Cells. Journal of Biological Chemistry.277: 24788-98.
D'Alonzo, R. C., et. al. (2002). Physical Interaction of the Activator Protein-1 Factors c-Fos and c-Jun with Cbfa1 for Collagenase-3 Promoter Activation. Journal of Biological Chemistry.277: 816-22.
D'Alonzo, R. C., et. al. (2002). Chapter 16: Bone Proteinases in Principles of Bone Biology. (Bilizekian, J. P., Raisz, L. G., and Rodan, G. A., eds), pp. 251-264, Academic Press Inc., San Diego, CA.
Swarthout, J.T., D'Alonzo, R. C., Selvamurugan, N., and Partridge, N.C. (2002). Regulation of Osteoblastic Gene Expression by Parathyroid Hormone. Gene.272:1-17.
Winchester, S.K., Selvamurugan, N., D'Alonzo, R. C., and Partridge, N.C. (2000). Developmental Regulation of Collagenase-3 mRNA in Normal, Differentiating Osteoblasts Through the Activator Protein-1 and the runt Domain Binding Sites. Journal of Biological Chemistry.275: 23310-18.
Ruh, M.F., Bi, Y., D'Alonzo, R.C., and Bellone (1998). Effects of Estrogens on IL-1b Promoter Activity. Journal of Steroid Biochemistry and Molecular Biology.4: 203-10
Gary John Mullen grew up in Southwestern Ohio, and attended Miami University at Oxford, where he received a BA in chemistry. He attended University of Cincinnati College of medicine and received the doctor of medicine degree in 1998. After completing an internship in obstetrics, Dr. Mullen was commissioned a Lieutenant in the United States navy, where he went on to serve multiple tours as a flight surgeon; first with VC-8 ("World Famous Redtails") in Ceiba, Puerto Rico, then with Carrier Training Air Wing Two (Kingsville, TX). It was during his tour in Kingsville that Dr. Mullen was hand-selected to be the 16th flight surgeon for the United States Navy Blue Angels, for the 2003-2004 Team. He went on to conclude a mishap-free tour, which included approximately 1000 Blue Angels flight demonstrations, in over 75 cities across the United States and Canada.
Dr. Mullen completed his residency in Anesthesia at Harvard Medical School, Brigham and Women's Hospital, in 2008. He was selected as a national FAER scholar by the Chair of his department. Upon graduating residency, he then attended the MIT Sloan School of Management as an Alfred P. Sloan Fellow, to obtain his MBA degree. While at MIT, Dr. Mullen led an entrepreneurship team to the semifinals of the 2009 MIT 100K Business Plan Competition with a technology application he helped develop involving rapid detection of disease proteins.
Dr. Mullen's current professional interests include human factors, product design, and commercializing the next-generation of innovative medical technologies. He is passionate about translating the clinical needs of new technologies into relevant commercial products.
Book Chapters and Published Journals
D'Alonzo RC, Gorrin-Rivas, MJ, Mackensen, GB. Chapter 5 - Three Dimensional Transesophageal Echocardiographic Planning. Robotic Cardiothoracic Surgery: Atlas and Guide. WR Chitwood and K Kernstein eds. (In press).
Gorrin-Rivas MJ, Dobra A, Simsir S, Dressman H, Mathew J, Schwinn D, Mackensen B, Newman M, Podgoreanu M. “Gene Expression Signatures of Atrial Fibrillation in Human Left Atrial Myocardium.”Anesth Analg 2007; 104:SCA42 (One of eight from 150 abstracts chosen for the 2007 Society of Cardiovascular Anesthesiologists Meeting, Montreal, Quebec “Expert Review of Best Abstracts Session”).
Gorrin-Rivas MJ, White WD, Mathew JP, Newman MF, Podgoreanu MV. “Serum Matrix Metalloproteinase 9 Levels and Incidence of Perioperative Atrial Fibrillation in Cardiac Surgery.” Anesth Analg 2007; 104:SCA65.
A. Nicoara, B. G. Phillips-Bute, M. Gorrin-Rivas, N. Nikolov, M. Swaminathan. “Determinants of Change in LV Diastolic Function after CABG Surgery.” Anesthesiology 2007; 107: A1230.
R. J. Pietras, M. Gorrin-Rivas, H-W. Chen. “Squalamine blocks tumor-associated angiogenesis and growth of ovarian cancer.” Int J Obstet Gynecol 2003; 83(Suppl 3):59–60.
Y. Ding, Y. Shimada, M. J. Gorrin-Rivas, A. Itami, Z. Li, T. Hong, M. Maeda, I. Komoto, A. Kawabe, J. Kaganoi, and M. Imamura. “Human macrophage metalloelastase expression in esophageal squamous cell carcinoma: its clinical significant relation with esophageal SCC.” Oncology 2002; 63:378-384.
M. J. Gorrin-Rivas, H-W. Chen, D. C. Marquez, and R. J. Pietras. “Squalamine blocks tumor associated angiogenesis and promotes antitumor effects of herceptin in HER-2/neu-overexpressing human breast cancer cells.” Proc Am Assoc Cancer Res 2002; 43:521-522.
M. J. Gorrin-Rivas, S. Arii, A. Mori, Y. Kaneda, and M. Imamura. “Mouse macrophage metalloelastase gene delivery by HVJ-cationic liposomes in experimental antiangiogenic gene therapy for murine CT-26 colon cancer.” Int J Cancer 2001; 93:731-735.
D. Chu, N. Kakazu, M. J. Gorrin-Rivas, H-P. Lu, M. Kawata, T. Abe, K. Ueda, and Y. Adachi. “Cloning and characterization of LUN, a novel RING-Finger Protein that is highly expressed in lung and specifically binds to a palindromic sequence.” J Biol Chem 2001; 276:14004-14013.
M. Minakuchi, N. Kakazu, M. J. Gorrin-Rivas, T. Abe, T. D. Copeland, K. Ueda, and Y. Adachi. “Identification and characterization of SEB, a novel protein that binds to the acute undifferentiated leukemia-associated protein SET.” Eur J Biochem 2001; 268:1340-1351.
W. Yang, S. Arii, M. J. Gorrin-Rivas, A. Mori, H. Onodera, and M. Imamura. “Human macrophage metalloelastase gene expression in colorectal cancer and its clinicopathological significance.” Cancer 2001; 91:1277-1283.
K. Furumoto, S. Arii, A. Mori, H. Furuyama, M. J. Gorrin Rivas, T. Nakao, N. Isobe, T. Murata, C. Takahashi, M. Noda, and M. Imamura. “RECK gene expression in hepatocellular carcinoma: correlation with invasion-related clinicopathological factors and its clinical significance.” Hepatology 2001; 33: 186-195
M. J. Gorrin-Rivas, S. Arii, A. Mori, and M. Imamura. “Macrophage metalloelastase gene associated to Hemagglutinating Virus of Japan (HVJ)-cationic liposomes: a novel antiangiogenic gene therapy for solid tumors.” Jpn J Gastroenterology 2000; 97 (suppl):A533.
A. Mori, S. Arii, M. Furutani, M. Mizumoto, S. Uchida, H. Furuyama, Y. Kondo, M. J. Gorrin-Rivas, K. Furumoto, Y. Kaneda, and M. Imamura. "Soluble Flt-1 gene therapy for peritoneal metastases using HVJ-cationic liposomes." Gene Ther 2000; 7: 1027-1033.
M. J. Gorrin-Rivas, S. Arii, M. Furutani, M. Mizumoto, A. Mori, K. Hanaki, M. Maeda, H. Furuyama, Y. Kondo, and M. Imamura. "Mouse macrophage metalloelastase gene transfer into a murine melanoma suppresses primary tumor growth by halting angiogenesis." Clin Cancer Res 2000; 6: 1647-1654.
M. J. Gorrin-Rivas, S. Arii, A. Mori, Y. Takeda, M. Mizumoto, M. Furutani, and M. Imamura. "Implications of human macrophage metalloelastase and vascular endothelial growth factor gene expression in angiogenesis of hepatocellular carcinoma." Ann Surg 2000; 231: 67-73.
Y. Takeda, S. Arii, T. Kaido, M. Niwano, T. Moriga, A. Mori, K. Hanaki, M. J. Gorrin-Rivas, T. Ishii, M. Sato, and M. Imamura. "Morphologic alteration of hepatocytes and sinusoidal endothelial cells in rat fatty liver during cold preservation and the protective effect of hepatocyte growth factor." Transplantation 1999; 67: 820-828.
A. Mori, S. Arii, M. Furutani, K. Hanaki, Y. Takeda, T. Moriga, Y. Kondo, M. J. Gorrin-Rivas, and M. Imamura. "Vascular endothelial growth factor-induced tumor angiogenesis and tumorigenicity in relation to metastasis in a HT1080 human fibrosarcoma cell model." Int J Cancer 1999; 80: 738-743.
M. J. Gorrin Rivas, S. Arii, M. Furutani, T. Harada, M. Mizumoto, H. Nishiyama, J. Fujita, and M. Imamura. "Expression of human macrophage metalloelastase gene in hepatocellular carcinoma: correlation with angiostatin generation and its clinical significance." Hepatology 1998; 28: 986-993.
Helle,R and Conlay, LA. Continuous Positive Airway Pressure. In N Singh-Radcliff et al. (ed) The 5-Minute Consult. LWW. Philidelphia, PA.
Helle, R.L. and McMurry, MB (2012, October) USE OF INHALED NITRIC OXIDE FOR ONE LUNG VENTILATION ON A PATIENT WITH SEVERE PULMONARY HYPERTENSION. Poster Presentation at ASA 2012. Washington D.C.
Helle, R.L. Marshall, JM. Stelzer, DC., and Younker, TD. (2012, October) STRESS-INDUCED (TAKOTSUBO) CARDIOMYOPATHY DIAGNOSED IN THE IMMEDIATE POST-OPERATIVE PERIOD. Poster Presentation at ASA 2012. Washington D.C.
Helle, R. and Fogel, S. (2012, March) HIGH SPINAL AFTER UNRECOGNIZED INTRATHECAL CATHETER PLACEMENT: EVERY DOSE IS A TEST DOSE. Midwest Anesthesia Resident Conference. Chicago, IL.
Helle, R. and Marshall, J. (2010, May) POST-OPERATIVE PVCs. Interesting Case Conference. Department of Anesthesiology, University of Missouri, Columbia, MO
Helle, R. and McMurry, M.. (2010 November) ONE LUNG VENTILATION ON A PATIENT WITH PULMONARY HYPERTENSION. Interesting Case Conference, Department of Anesthesiology, University of Missouri, Columbia, MO
Helle, R.,. Legg, R., Legg, M.,. (2004, April) LEAD CONCENTRATION OF LIVER TISSUE FROM PEROMYSCUS LEUCOPUS AT NAHANT MARSH. First Annual Scientific Research Symposium at Nahant Marsh; Davenport, IA
Helle, R., and Bubar, M., Cunningham, K..(2004, August) ANALYSIS OF SEROTONIN 2C RECEPTIOR AND TUBBY PROTEIN LEVELS FOLLOWING REPEATED EXPOSURE TO (+)-MDMA OR THE 5-HT2CR AGONIST. Summer Undergraduate Research Program Poster Session; Galveston, TX
American Society of Regional Anesthesia and Pain Medicine
Dong M, Ding X-Q, Thomas SE, Gao F, Lam PCH, Abagyan R, Miller LJ. Role of lysine187 within the second extracellular loop of the type A cholecystokinin receptor in agonist-induced activation. Use of complementary charge-reversal mutagenesis to define a functionally important interdomain interaction. Biochemistry 46:4522-4531, 2007.
“An Overview of Ultrasound-Guided Regional Anesthesia: Upper Extremity” “An Overview of Ultrasound-Guided Regional Anesthesia: Lower Extremity” American Academy of Anesthesiologist Assistants 38th Annual Meeting, Hilton Head, SC (April 2014)
“Characterization of Novel Opioid Glycolipopeptide Analgesics” Rocky Mountain Neuroscience Group Meeting University of Colorado Health Sciences Center, Denver, CO (May 2001)
“Exploration of the Role of Charged Residue in the Second Loop of the Cholecystokinin Receptor in Position 187” Molecular Pharmacology and Experimental Therapeutics Conference Mayo Clinic and Foundation, Rochester, MN (August 2001)